Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation

Chronic inflammation is linked to diverse disease processes, but the intrinsic mechanisms that determine cellular sensitivity to inflammation are incompletely understood. Here, we show the contribution of glucose metabolism to inflammation-induced changes in the survival of pancreatic islet β-cells....

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Detalles Bibliográficos
Autores principales: Fu, Accalia, Alvarez-Perez, Juan Carlos, Avizonis, Daina, Kin, Tatsuya, Ficarro, Scott B., Choi, Dong Wook, Karakose, Esra, Badur, Mehmet G., Evans, Lindsay, Rosselot, Carolina, Bridon, Gaelle, Bird, Gregory H., Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Kamphorst, Jurre J., Stewart, Andrew F., Shapiro, A. M. James, Marto, Jarrod A., Walensky, Loren D., Jones, Russell G., Garcia-Ocana, Adolfo, Danial, Nika N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568475/
https://www.ncbi.nlm.nih.gov/pubmed/32694660
http://dx.doi.org/10.1038/s42255-020-0199-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568475/
https://www.ncbi.nlm.nih.gov/pubmed/32694660
http://dx.doi.org/10.1038/s42255-020-0199-4

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