Cargando…
Caspase inhibition rescues F1Fo ATP synthase dysfunction-mediated dendritic spine elimination
Dendritic spine injury underlies synaptic failure in many neurological disorders. Mounting evidence suggests a mitochondrial pathway of local nonapoptotic caspase signaling in mediating spine pruning. However, it remains unclear whether this caspase signaling plays a key role in spine loss when seve...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568535/ https://www.ncbi.nlm.nih.gov/pubmed/33067541 http://dx.doi.org/10.1038/s41598-020-74613-9 |