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Caspase inhibition rescues F1Fo ATP synthase dysfunction-mediated dendritic spine elimination

Dendritic spine injury underlies synaptic failure in many neurological disorders. Mounting evidence suggests a mitochondrial pathway of local nonapoptotic caspase signaling in mediating spine pruning. However, it remains unclear whether this caspase signaling plays a key role in spine loss when seve...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Tian, Jing, Guo, Lan, Du, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568535/
https://www.ncbi.nlm.nih.gov/pubmed/33067541
http://dx.doi.org/10.1038/s41598-020-74613-9