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Caspase inhibition rescues F1Fo ATP synthase dysfunction-mediated dendritic spine elimination
Dendritic spine injury underlies synaptic failure in many neurological disorders. Mounting evidence suggests a mitochondrial pathway of local nonapoptotic caspase signaling in mediating spine pruning. However, it remains unclear whether this caspase signaling plays a key role in spine loss when seve...
Autores principales: | Chen, Hao, Tian, Jing, Guo, Lan, Du, Heng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568535/ https://www.ncbi.nlm.nih.gov/pubmed/33067541 http://dx.doi.org/10.1038/s41598-020-74613-9 |
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