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HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse

Excessive intake of fat causes accumulation of fat in liver, leading to non-alcoholic fatty liver disease (NAFLD). High-fat diet (HFD) upregulates the expression of Factor D, a complement pathway component, in the liver of mice. However, the functions of Factor D in liver are not well known. Therefo...

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Detalles Bibliográficos
Autores principales: Tsuru, Hiromi, Osaka, Mizuko, Hiraoka, Yuichi, Yoshida, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568538/
https://www.ncbi.nlm.nih.gov/pubmed/33067533
http://dx.doi.org/10.1038/s41598-020-74617-5