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HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse
Excessive intake of fat causes accumulation of fat in liver, leading to non-alcoholic fatty liver disease (NAFLD). High-fat diet (HFD) upregulates the expression of Factor D, a complement pathway component, in the liver of mice. However, the functions of Factor D in liver are not well known. Therefo...
Autores principales: | Tsuru, Hiromi, Osaka, Mizuko, Hiraoka, Yuichi, Yoshida, Masayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568538/ https://www.ncbi.nlm.nih.gov/pubmed/33067533 http://dx.doi.org/10.1038/s41598-020-74617-5 |
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