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Long noncoding RNA PVT1 promoted gallbladder cancer proliferation by epigenetically suppressing miR-18b-5p via DNA methylation

Gallbladder cancer (GBC) accounts for 85–90% malignancies of the biliary tree worldwide. Considerable evidence has demonstrated that dysregulation of lncRNAs is involved in the progression of cancer. LncRNA PVT1 has been reported to play important roles in various cancers, but its role in gallbladde...

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Detalles Bibliográficos
Autores principales: Jin, Longyang, Cai, Qiang, Wang, Shouhua, Wang, Shuqing, Wang, Jiandong, Quan, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568542/
https://www.ncbi.nlm.nih.gov/pubmed/33067424
http://dx.doi.org/10.1038/s41419-020-03080-x