Evaluation of the antitumor effects of PP242 in a colon cancer xenograft mouse model using comprehensive metabolomics and lipidomics

PP242, an inhibitor of mechanistic target of rapamycin (mTOR), displays potent anticancer effects against various cancer types. However, the underlying metabolic mechanism associated with the PP242 effects is not clearly understood. In this study, comprehensive metabolomics and lipidomics investigat...

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Detalles Bibliográficos
Autores principales: Rashid, Md Mamunur, Lee, Hyunbeom, Jung, Byung Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568555/
https://www.ncbi.nlm.nih.gov/pubmed/33067464
http://dx.doi.org/10.1038/s41598-020-73721-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568555/
https://www.ncbi.nlm.nih.gov/pubmed/33067464
http://dx.doi.org/10.1038/s41598-020-73721-w

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