Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin

Global emergence of Gram-negative bacteria carrying the plasmid-borne resistance genes, bla(MBL) and mcr, raises a significant challenge to the treatment of life-threatening infections by the antibiotics, carbapenem and colistin (COL). Here, we identify an antirheumatic drug, auranofin (AUR) as a du...

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Detalles Bibliográficos
Autores principales: Sun, Hongzhe, Zhang, Qi, Wang, Runming, Wang, Haibo, Wong, Yuen-Ting, Wang, Minji, Hao, Quan, Yan, Aixin, Kao, Richard Yi-Tsun, Ho, Pak-Leung, Li, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568570/
https://www.ncbi.nlm.nih.gov/pubmed/33067430
http://dx.doi.org/10.1038/s41467-020-18939-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568570/
https://www.ncbi.nlm.nih.gov/pubmed/33067430
http://dx.doi.org/10.1038/s41467-020-18939-y

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