ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo

Signs of proteostasis failure often entwine with those of metabolic stress at the cellular level. Here, we study protein sequestration during glucose deprivation-induced ATP decline in Saccharomyces cerevisiae. Using live-cell imaging, we find that sequestration of misfolded proteins and nascent pol...

Descripción completa

Detalles Bibliográficos
Autores principales: Sathyanarayanan, Udhayabhaskar, Musa, Marina, Bou Dib, Peter, Raimundo, Nuno, Milosevic, Ira, Krisko, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568574/
https://www.ncbi.nlm.nih.gov/pubmed/33067463
http://dx.doi.org/10.1038/s41467-020-19104-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568574/
https://www.ncbi.nlm.nih.gov/pubmed/33067463
http://dx.doi.org/10.1038/s41467-020-19104-1

Ejemplares similares