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ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo
Signs of proteostasis failure often entwine with those of metabolic stress at the cellular level. Here, we study protein sequestration during glucose deprivation-induced ATP decline in Saccharomyces cerevisiae. Using live-cell imaging, we find that sequestration of misfolded proteins and nascent pol...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568574/ https://www.ncbi.nlm.nih.gov/pubmed/33067463 http://dx.doi.org/10.1038/s41467-020-19104-1 |