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Upregulation of nAChRs and Changes in Excitability on VTA Dopamine and GABA Neurons Correlates to Changes in Nicotine-Reward-Related Behavior

Previous reports indicate that nicotine reward is mediated through α4β2*, α6β2*, and α4α6β2* nicotinic acetylcholine receptors (nAChRs; * indicates that additional nAChR subunits may be present). Little is known about α4α6β2* nAChR involvement in reward and reinforcement because of a lack of methods...

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Detalles Bibliográficos
Autores principales: Akers, Austin T., Cooper, Skylar Y., Baumgard, Zachary J., Casinelli, Gabriella P., Avelar, Alicia J., Henderson, Brandon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568605/
https://www.ncbi.nlm.nih.gov/pubmed/32988984
http://dx.doi.org/10.1523/ENEURO.0189-20.2020