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EGCG Upregulates UCP(3) Levels to Protect MIN(6) Pancreatic Islet Cells from Interleukin-1β-Induced Apoptosis

OBJECTIVE: The protective effects of epigallocatechin gallate (EGCG) on interleukin-1β (IL-1β)-induced apoptosis were investigated in murine MIN(6) pancreatic β-cells. The role of uncoupling protein-3 (UCP(3)) signaling in this process was also explored. METHODS: After treatment with IL-1β and EGCG,...

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Detalles Bibliográficos
Autores principales: Jia, Xu, Luo, Ziren, Gao, Ying, Liu, Hua, Liu, Xinghai, Mai, Wenli, Liu, Hong, Zheng, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568641/
https://www.ncbi.nlm.nih.gov/pubmed/33116413
http://dx.doi.org/10.2147/DDDT.S270345