Aberrant super-enhancer landscape reveals core transcriptional regulatory circuitry in lung adenocarcinoma

Lung adenocarcinoma (LUAD) relies on dysregulated gene expression to sustain its infinite growth and progression. Emerging evidence indicates that aberrant transcriptional program results from core transcriptional regulatory circuitry (CRC) which is driven by super-enhancers (SEs). In this study, by...

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Detalles Bibliográficos
Autores principales: Zhang, Te, Song, Xuming, Zhang, Zeyu, Mao, Qixing, Xia, Wenjie, Xu, Lin, Jiang, Feng, Dong, Gaochao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568720/
https://www.ncbi.nlm.nih.gov/pubmed/33070167
http://dx.doi.org/10.1038/s41389-020-00277-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568720/
https://www.ncbi.nlm.nih.gov/pubmed/33070167
http://dx.doi.org/10.1038/s41389-020-00277-9

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