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Amitriptyline interferes with autophagy-mediated clearance of protein aggregates via inhibiting autophagosome maturation in neuronal cells
Amitriptyline is a tricyclic antidepressant commonly prescribed for major depressive disorders, as well as depressive symptoms associated with various neurological disorders. A possible correlation between the use of tricyclic antidepressants and the occurrence of Parkinson’s disease has been report...
Autores principales: | Kwon, Yoonjung, Bang, Yeojin, Moon, Soung-Hee, Kim, Aeri, Choi, Hyun Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568721/ https://www.ncbi.nlm.nih.gov/pubmed/33070168 http://dx.doi.org/10.1038/s41419-020-03085-6 |
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