Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila

BACKGROUND: Self-assembly of the amyloid-β (Aβ) peptide into aggregates, from small oligomers to amyloid fibrils, is fundamentally linked with Alzheimer’s disease (AD). However, it is clear that not all forms of Aβ are equally harmful and that linking a specific aggregate to toxicity also depends on...

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Detalles Bibliográficos
Autores principales: De Mena, Lorena, Smith, Michael A., Martin, Jason, Dunton, Katie L., Ceballos-Diaz, Carolina, Jansen-West, Karen R., Cruz, Pedro E., Dillon, Kristy D., Rincon-Limas, Diego E., Golde, Todd E., Moore, Brenda D., Levites, Yona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568834/
https://www.ncbi.nlm.nih.gov/pubmed/33069251
http://dx.doi.org/10.1186/s13195-020-00698-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568834/
https://www.ncbi.nlm.nih.gov/pubmed/33069251
http://dx.doi.org/10.1186/s13195-020-00698-z

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