Low‐glucose‐sensitive TRPC6 dysfunction drives hypoglycemia‐induced cognitive impairment in diabetes

BACKGROUND: Recurrent moderate hypoglycemia (RH), a major adverse effect of hypoglycemic therapy in diabetic patients, is one of the main risk factors for cognitive impairment and dementia. Transient receptor potential canonical channel 6 (TRPC6) is a potential therapeutic target for Alzheimer'...

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Detalles Bibliográficos
Autores principales: He, Chengkang, Gao, Peng, Cui, Yuanting, Li, Qiang, Li, Yingsha, Lu, Zongshi, Ma, Huan, Zhao, Yu, Li, Li, Sun, Fang, Chen, Xiaowei, Jia, Hongbo, Liu, Daoyan, Yang, Gangyi, Zheng, Hongting, Zhu, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568851/
https://www.ncbi.nlm.nih.gov/pubmed/33135341
http://dx.doi.org/10.1002/ctm2.205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568851/
https://www.ncbi.nlm.nih.gov/pubmed/33135341
http://dx.doi.org/10.1002/ctm2.205

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