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Low‐glucose‐sensitive TRPC6 dysfunction drives hypoglycemia‐induced cognitive impairment in diabetes
BACKGROUND: Recurrent moderate hypoglycemia (RH), a major adverse effect of hypoglycemic therapy in diabetic patients, is one of the main risk factors for cognitive impairment and dementia. Transient receptor potential canonical channel 6 (TRPC6) is a potential therapeutic target for Alzheimer'...
Autores principales: | He, Chengkang, Gao, Peng, Cui, Yuanting, Li, Qiang, Li, Yingsha, Lu, Zongshi, Ma, Huan, Zhao, Yu, Li, Li, Sun, Fang, Chen, Xiaowei, Jia, Hongbo, Liu, Daoyan, Yang, Gangyi, Zheng, Hongting, Zhu, Zhiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568851/ https://www.ncbi.nlm.nih.gov/pubmed/33135341 http://dx.doi.org/10.1002/ctm2.205 |
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