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Role of the CXCR4/ALK5/Smad3 Signaling Pathway in Cancer-Induced Bone Pain

PURPOSE: The chemokine receptor, CXCR4, and the transforming growth factor-beta receptor, ALK5, both contribute to various processes associated with the sensation of pain. However, the relationship between CXCR4 and ALK5 and the possible mechanisms promoted by ALK5 in the development of pain have no...

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Detalles Bibliográficos
Autores principales: Peng, Chong, Chen, Xue-Tai, Xu, Heng, Chen, Li-Ping, Shen, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569080/
https://www.ncbi.nlm.nih.gov/pubmed/33116799
http://dx.doi.org/10.2147/JPR.S260508