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Differential sensitivity of acute myeloid leukemia cells to daunorubicin depends on P2X7A versus P2X7B receptor expression

Acute myeloid leukemia (AML) is a common adult leukemia often arising from a preexistent myelodysplastic syndrome (MDS). High mortality rates of AML are caused by relapse and chemoresistance; therefore, we analyzed the role of P2X7 receptor (P2X7R) splice variants A and B in AML progression and resp...

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Detalles Bibliográficos
Autores principales: Pegoraro, Anna, Orioli, Elisa, De Marchi, Elena, Salvestrini, Valentina, Milani, Asia, Di Virgilio, Francesco, Curti, Antonio, Adinolfi, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569086/
https://www.ncbi.nlm.nih.gov/pubmed/33071281
http://dx.doi.org/10.1038/s41419-020-03058-9