Cargando…
Differential sensitivity of acute myeloid leukemia cells to daunorubicin depends on P2X7A versus P2X7B receptor expression
Acute myeloid leukemia (AML) is a common adult leukemia often arising from a preexistent myelodysplastic syndrome (MDS). High mortality rates of AML are caused by relapse and chemoresistance; therefore, we analyzed the role of P2X7 receptor (P2X7R) splice variants A and B in AML progression and resp...
Autores principales: | Pegoraro, Anna, Orioli, Elisa, De Marchi, Elena, Salvestrini, Valentina, Milani, Asia, Di Virgilio, Francesco, Curti, Antonio, Adinolfi, Elena |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569086/ https://www.ncbi.nlm.nih.gov/pubmed/33071281 http://dx.doi.org/10.1038/s41419-020-03058-9 |
Ejemplares similares
-
The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment
por: De Marchi, Elena, et al.
Publicado: (2019) -
Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells
por: Salvestrini, Valentina, et al.
Publicado: (2016) -
P2X7 Variants in Oncogenesis
por: Pegoraro, Anna, et al.
Publicado: (2021) -
P2X7 Receptor in Hematological Malignancies
por: De Marchi, Elena, et al.
Publicado: (2021) -
A2A Receptor Contributes to Tumor Progression in P2X7 Null Mice
por: De Marchi, Elena, et al.
Publicado: (2022)