Optimization of expression and purification of mitochondrial HSP 40 (Tid1-L) chaperone: Role of mortalin and tid1 in the reactivation and amyloid inhibition of proteins

Stimulation of complex chaperone activity may be a viable means of therapy for neurodegenerative diseases. These chaperons execute reactivation of thermally and chemically aggregated protein substrates by cooperating with their partner co-chaperons. We optimized the expression and purification condi...

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Detalles Bibliográficos
Autores principales: Khan, Mohammad Rashid, Khan, Mohd Shahnawaz, Ahmed, Anwar, Malik, Ajamaluddin, Qamar, Wajhul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569118/
https://www.ncbi.nlm.nih.gov/pubmed/33100870
http://dx.doi.org/10.1016/j.sjbs.2020.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569118/
https://www.ncbi.nlm.nih.gov/pubmed/33100870
http://dx.doi.org/10.1016/j.sjbs.2020.09.006

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