Cargando…

Inhaled dry powder alginate oligosaccharide in cystic fibrosis: a randomised, double-blind, placebo-controlled, crossover phase 2b study

BACKGROUND: OligoG is a low molecular-weight alginate oligosaccharide that improves the viscoelastic properties of cystic fibrosis (CF) mucus and disrupts biofilms, thereby potentiating the activity of antimicrobial agents. The efficacy of inhaled OligoG was evaluated in adult patients with CF. METH...

Descripción completa

Detalles Bibliográficos
Autores principales: van Koningsbruggen-Rietschel, Silke, Davies, Jane C., Pressler, Tacjana, Fischer, Rainald, MacGregor, Gordon, Donaldson, Scott H., Smerud, Knut, Meland, Nils, Mortensen, Jann, Fosbøl, Marie Ø., Downey, Damian G., Myrset, Astrid H., Flaten, Hugo, Rye, Philip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569163/
https://www.ncbi.nlm.nih.gov/pubmed/33123558
http://dx.doi.org/10.1183/23120541.00132-2020