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Durable Response to Osimertinib in a Chinese Patient with Metastatic Lung Adenocarcinoma Harboring a Rare EGFR L858R/D761Y Compound Mutation

Uncommon mutations account for 10–15% of epidermal growth factor receptor (EGFR) mutations in patients with non-small-cell lung cancer (NSCLC). However, in spite of the wealth of knowledge of the clinical significance and tyrosine kinase inhibitor (TKI) sensitivity of these mutations, acquisition of...

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Detalles Bibliográficos
Autores principales: Zhu, Yajie, Tang, Jianning, Li, Xin, Qin, Tian, Wei, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569175/
https://www.ncbi.nlm.nih.gov/pubmed/33116624
http://dx.doi.org/10.2147/OTT.S268593