Development and Optimization of a Hydrophobic Interaction Chromatography-Based Method of AAV Harvest, Capture, and Recovery

With many ongoing clinical trials utilizing adeno-associated virus (AAV) gene therapy, it is necessary to find scalable and serotype-independent primary capture and recovery methods to allow for efficient and robust manufacturing processes. Here, we demonstrate the ability of a hydrophobic interacti...

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Detalles Bibliográficos
Autores principales: McNally, David J., Piras, Bryan A., Willis, Catherine M., Lockey, Timothy D., Meagher, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569186/
https://www.ncbi.nlm.nih.gov/pubmed/33102619
http://dx.doi.org/10.1016/j.omtm.2020.09.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569186/
https://www.ncbi.nlm.nih.gov/pubmed/33102619
http://dx.doi.org/10.1016/j.omtm.2020.09.015

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