RasGRP1 induces autophagy and transformation-associated changes in primary human keratinocytes

Ras mutations are present in only a subset of sporadic human cutaneous squamous cell carcinomas (cSCC) even though Ras is activated in most. This suggests that other mechanisms of Ras activation play a role in the disease. The aberrant expression of RasGRP1, a guanyl nucleotide exchange factor for R...

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Detalles Bibliográficos
Autores principales: Fonseca, Lauren L., Yang, Won Seok, Geerts, Dirk, Turkson, James, Ji, Junfang, Ramos, Joe W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569238/
https://www.ncbi.nlm.nih.gov/pubmed/33074128
http://dx.doi.org/10.1016/j.tranon.2020.100880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569238/
https://www.ncbi.nlm.nih.gov/pubmed/33074128
http://dx.doi.org/10.1016/j.tranon.2020.100880

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