RNA-sequencing of IDH-wild-type glioblastoma with chromothripsis identifies novel gene fusions with potential oncogenic properties

Glioblastoma (GBM) is the most frequent and most aggressive form of glioma. It is characterized by marked genomic instability, which suggests that chromothripsis (CT) might be involved in GBM initiation. Recently, CT has emerged as an alternative mechanism of cancer development, involving massive ch...

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Detalles Bibliográficos
Autores principales: Ah-Pine, Franck, Casas, Déborah, Menei, Philippe, Boisselier, Blandine, Garcion, Emmanuel, Rousseau, Audrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569239/
https://www.ncbi.nlm.nih.gov/pubmed/33074125
http://dx.doi.org/10.1016/j.tranon.2020.100884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569239/
https://www.ncbi.nlm.nih.gov/pubmed/33074125
http://dx.doi.org/10.1016/j.tranon.2020.100884

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