Metformin Increases the Chemosensitivity of Pancreatic Cancer Cells to Gemcitabine by Reversing EMT Through Regulation DNA Methylation of miR-663

BACKGROUND: Pancreatic cancer is a devastating malignancy with poor prognosis. Metformin, a classic anti-diabetes drug, seems to improve survival of pancreatic cancer patients in some studies. METHODS: Cell counting kit-8 assay was used to detect the BxPC-3 and MIAPaCa-2 cell viability after treatme...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Yuqing, Zhang, Bin, Gu, Guangliang, Yang, Xiaojun, Qian, Zhuyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569251/
https://www.ncbi.nlm.nih.gov/pubmed/33116621
http://dx.doi.org/10.2147/OTT.S261570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569251/
https://www.ncbi.nlm.nih.gov/pubmed/33116621
http://dx.doi.org/10.2147/OTT.S261570

Ejemplares similares