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Metformin Increases the Chemosensitivity of Pancreatic Cancer Cells to Gemcitabine by Reversing EMT Through Regulation DNA Methylation of miR-663

BACKGROUND: Pancreatic cancer is a devastating malignancy with poor prognosis. Metformin, a classic anti-diabetes drug, seems to improve survival of pancreatic cancer patients in some studies. METHODS: Cell counting kit-8 assay was used to detect the BxPC-3 and MIAPaCa-2 cell viability after treatme...

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Detalles Bibliográficos
Autores principales:	Gu, Yuqing, Zhang, Bin, Gu, Guangliang, Yang, Xiaojun, Qian, Zhuyin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569251/ https://www.ncbi.nlm.nih.gov/pubmed/33116621 http://dx.doi.org/10.2147/OTT.S261570

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