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Formulation and in vitro Evaluation of Fast Dissolving Tablets of Febuxostat Using Co-Processed Excipients

BACKGROUND: Febuxostat is a novel, orally-administered, powerful, non-purine, xanthine oxidase inhibitor used for treating gout and ceaseless tophaceous gout. The drug exhibits low bioavailability (about 49%) which is ascribed to its dissolution rate-limited absorption. OBJECTIVE: The current work i...

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Detalles Bibliográficos
Autores principales: Kaur, Manpreet, Mittal, Amit, Gulati, Monica, Sharma, Deepika, Kumar, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569284/
https://www.ncbi.nlm.nih.gov/pubmed/31884935
http://dx.doi.org/10.2174/1872211314666191224121044