Partial Replacement of Nucleosomal DNA with Human FACT Induces Dynamic Exposure and Acetylation of Histone H3 N-Terminal Tails

The FACT (facilitates chromatin transcription) complex, comprising SPT16 and SSRP1, conducts structural alterations during nucleosome unwrapping. Our previous cryoelectron microscopic (cryo-EM) analysis revealed the first intermediate structure of an unwrapped nucleosome with human FACT, in which 11...

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Detalles Bibliográficos
Autores principales: Tsunaka, Yasuo, Ohtomo, Hideaki, Morikawa, Kosuke, Nishimura, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569332/
https://www.ncbi.nlm.nih.gov/pubmed/33103079
http://dx.doi.org/10.1016/j.isci.2020.101641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569332/
https://www.ncbi.nlm.nih.gov/pubmed/33103079
http://dx.doi.org/10.1016/j.isci.2020.101641

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