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Location Bias as Emerging Paradigm in GPCR Biology and Drug Discovery

GPCRs are the largest receptor family that are involved in virtually all biological processes. Pharmacologically, they are highly druggable targets, as they cover more than 40% of all drugs in the market. Our knowledge of biased signaling provided insight into pharmacology vastly improving drug desi...

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Detalles Bibliográficos
Autores principales: Mohammad Nezhady, Mohammad Ali, Rivera, José Carlos, Chemtob, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569339/
https://www.ncbi.nlm.nih.gov/pubmed/33103080
http://dx.doi.org/10.1016/j.isci.2020.101643