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Location Bias as Emerging Paradigm in GPCR Biology and Drug Discovery
GPCRs are the largest receptor family that are involved in virtually all biological processes. Pharmacologically, they are highly druggable targets, as they cover more than 40% of all drugs in the market. Our knowledge of biased signaling provided insight into pharmacology vastly improving drug desi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569339/ https://www.ncbi.nlm.nih.gov/pubmed/33103080 http://dx.doi.org/10.1016/j.isci.2020.101643 |