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Patient-derived malignant pleural mesothelioma cell cultures: a tool to advance biomarker-driven treatments

Malignant pleural mesothelioma (MPM) is an aggressive cancer, associated with poor prognosis. We assessed the feasibility of patient-derived cell cultures to serve as an ex vivo model of MPM. Patient-derived MPM cell cultures (n=16) exhibited stemness features and reflected intratumour and interpati...

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Detalles Bibliográficos
Autores principales: Kanellakis, Nikolaos I, Asciak, Rachelle, Hamid, Megat Abd, Yao, Xuan, McCole, Mark, McGowan, Simon, Seraia, Elena, Hatch, Stephanie, Hallifax, Rob J, Mercer, Rachel M, Bedawi, Eihab O, Jones, Stephanie, Verrill, Clare, Dobson, Melissa, George, Vineeth, Stathopoulos, Georgios T, Peng, Yanchun, Ebner, Daniel, Dong, Tao, Rahman, Najib M, Psallidas, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569377/
https://www.ncbi.nlm.nih.gov/pubmed/32943495
http://dx.doi.org/10.1136/thoraxjnl-2020-215027