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Data-driven evolution of neurosurgical gene therapy delivery in Parkinson’s disease

Loss of nigrostriatal dopaminergic projection neurons is a key pathology in Parkinson’s disease, leading to abnormal function of basal ganglia motor circuits and the accompanying characteristic motor features. A number of intraparenchymally delivered gene therapies designed to modify underlying dise...

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Detalles Bibliográficos
Autores principales: Richardson, R Mark, Bankiewicz, Krystof S, Christine, Chadwick W, Van Laar, Amber D, Gross, Robert E, Lonser, Russell, Factor, Stewart A, Kostyk, Sandra K, Kells, Adrian P, Ravina, Bernard, Larson, Paul S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569395/
https://www.ncbi.nlm.nih.gov/pubmed/32732384
http://dx.doi.org/10.1136/jnnp-2020-322904