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Data-driven evolution of neurosurgical gene therapy delivery in Parkinson’s disease
Loss of nigrostriatal dopaminergic projection neurons is a key pathology in Parkinson’s disease, leading to abnormal function of basal ganglia motor circuits and the accompanying characteristic motor features. A number of intraparenchymally delivered gene therapies designed to modify underlying dise...
Autores principales: | Richardson, R Mark, Bankiewicz, Krystof S, Christine, Chadwick W, Van Laar, Amber D, Gross, Robert E, Lonser, Russell, Factor, Stewart A, Kostyk, Sandra K, Kells, Adrian P, Ravina, Bernard, Larson, Paul S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569395/ https://www.ncbi.nlm.nih.gov/pubmed/32732384 http://dx.doi.org/10.1136/jnnp-2020-322904 |
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