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CEN‐tools: an integrative platform to identify the contexts of essential genes

An emerging theme from large‐scale genetic screens that identify genes essential for cell fitness is that essentiality of a given gene is highly context‐specific. Identification of such contexts could be the key to defining gene function and also to develop novel therapeutic interventions. Here, we...

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Detalles Bibliográficos
Autores principales: Sharma, Sumana, Dincer, Cansu, Weidemüller, Paula, Wright, Gavin J, Petsalaki, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569414/
https://www.ncbi.nlm.nih.gov/pubmed/33073517
http://dx.doi.org/10.15252/msb.20209698