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Protective Effects of Two Safflower Derived Compounds, Kaempferol and Hydroxysafflor Yellow A, on Hyperglycaemic Stress-Induced Podocyte Apoptosis via Modulating of Macrophage M1/M2 Polarization

OBJECTIVE: The primary initiating mechanism in diabetes nephropathy (DN) is hyperglycemia-induced inflammation in which macrophage and podocyte play important roles. The present research is aimed at exploring the effects of kaempferol (Ka) and hydroxysafflor yellow A (HSYA) on classically activated...

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Detalles Bibliográficos
Autores principales: Li, Yuanping, Zheng, Dan, Shen, Dayue, Zhang, Xilan, Zhao, Xiaoyun, Liao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569436/
https://www.ncbi.nlm.nih.gov/pubmed/33102606
http://dx.doi.org/10.1155/2020/2462039