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Metabolic Characterization and Consequences of Mitochondrial Pyruvate Carrier Deficiency in Drosophila melanogaster

In insect, pyruvate is generally the predominant oxidative substrate for mitochondria. This metabolite is transported inside mitochondria via the mitochondrial pyruvate carrier (MPC), but whether and how this transporter controls mitochondrial oxidative capacities in insects is still relatively unkn...

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Detalles Bibliográficos
Autores principales: Simard, Chloé, Lebel, Andréa, Allain, Eric Pierre, Touaibia, Mohamed, Hebert-Chatelain, Etienne, Pichaud, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570025/
https://www.ncbi.nlm.nih.gov/pubmed/32899962
http://dx.doi.org/10.3390/metabo10090363