Impact of Surfactant Protein-A Variants on Survival in Aged Mice in Response to Klebsiella pneumoniae Infection and Ozone: Serendipity in Action

Innate immune molecules, SP-A1 (6A(2), 6A(4)) and SP-A2 (1A(0), 1A(3)), differentially affect young mouse survival after infection. Here, we investigated the impact of SP-A variants on the survival of aged mice. hTG mice carried a different SP-A1 or SP-A2 variant and SP-A-KO were either infected wit...

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Detalles Bibliográficos
Autores principales: Thorenoor, Nithyananda, S. Phelps, David, Kala, Padma, Ravi, Radhika, Floros Phelps, Andreas, M. Umstead, Todd, Zhang, Xuesheng, Floros, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570056/
https://www.ncbi.nlm.nih.gov/pubmed/32825654
http://dx.doi.org/10.3390/microorganisms8091276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570056/
https://www.ncbi.nlm.nih.gov/pubmed/32825654
http://dx.doi.org/10.3390/microorganisms8091276

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