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NFATc2-dependent epigenetic upregulation of CXCL14 is involved in the development of neuropathic pain induced by paclitaxel

BACKGROUND: The major dose-limiting toxicity of paclitaxel, one of the most commonly used drugs to treat solid tumor, is painful neuropathy. However, the molecular mechanisms underlying paclitaxel-induced painful neuropathy are largely unclarified. METHODS: Paw withdrawal threshold was measured in t...

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Detalles Bibliográficos
Autores principales: Liu, Meng, Zhang, Su-Bo, Luo, Yu-Xuan, Yang, Yan-Ling, Zhang, Xiang-Zhong, Li, Bo, Meng, Yan, Chen, Yuan-Jie, Guo, Rui-Xian, Xiong, Yuan-Chang, Xin, Wen-Jun, Li, Dai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570122/
https://www.ncbi.nlm.nih.gov/pubmed/33070779
http://dx.doi.org/10.1186/s12974-020-01992-1