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Neuroprotective effects of verbascoside against Alzheimer’s disease via the relief of endoplasmic reticulum stress in Aβ-exposed U251 cells and APP/PS1 mice

BACKGROUND: Endoplasmic reticulum (ER) stress is involved in the progression of Alzheimer’s disease (AD). Verbascoside (VB), an active phenylethanoid glycoside that was first isolated from Verbascum sinuatum (the wavyleaf mullein), possesses anti-inflammatory, antioxidative, and anti-apoptotic effec...

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Detalles Bibliográficos
Autores principales: Wang, Chunyue, Cai, Xueying, Wang, Ruochen, Zhai, Siyu, Zhang, Yongfeng, Hu, Wenji, Zhang, Yizhi, Wang, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570123/
https://www.ncbi.nlm.nih.gov/pubmed/33070776
http://dx.doi.org/10.1186/s12974-020-01976-1