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Neuroprotective effects of verbascoside against Alzheimer’s disease via the relief of endoplasmic reticulum stress in Aβ-exposed U251 cells and APP/PS1 mice
BACKGROUND: Endoplasmic reticulum (ER) stress is involved in the progression of Alzheimer’s disease (AD). Verbascoside (VB), an active phenylethanoid glycoside that was first isolated from Verbascum sinuatum (the wavyleaf mullein), possesses anti-inflammatory, antioxidative, and anti-apoptotic effec...
Autores principales: | Wang, Chunyue, Cai, Xueying, Wang, Ruochen, Zhai, Siyu, Zhang, Yongfeng, Hu, Wenji, Zhang, Yizhi, Wang, Di |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570123/ https://www.ncbi.nlm.nih.gov/pubmed/33070776 http://dx.doi.org/10.1186/s12974-020-01976-1 |
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