Cargando…

Neuroprotective effects of verbascoside against Alzheimer’s disease via the relief of endoplasmic reticulum stress in Aβ-exposed U251 cells and APP/PS1 mice

BACKGROUND: Endoplasmic reticulum (ER) stress is involved in the progression of Alzheimer’s disease (AD). Verbascoside (VB), an active phenylethanoid glycoside that was first isolated from Verbascum sinuatum (the wavyleaf mullein), possesses anti-inflammatory, antioxidative, and anti-apoptotic effec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Chunyue, Cai, Xueying, Wang, Ruochen, Zhai, Siyu, Zhang, Yongfeng, Hu, Wenji, Zhang, Yizhi, Wang, Di
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570123/ https://www.ncbi.nlm.nih.gov/pubmed/33070776 http://dx.doi.org/10.1186/s12974-020-01976-1

Ejemplares similares

Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice
por: Li, Zhiping, et al.
Publicado: (2021)

[Corrigendum] Neuroprotective effect of emodin against Alzheimer’s disease via Nrf2 signaling in U251 cells and APP/PS1 mice
por: Li, Zhiping, et al.
Publicado: (2023)

The Neuroprotection of Verbascoside in Alzheimer’s Disease Mediated through Mitigation of Neuroinflammation via Blocking NF-κB-p65 Signaling
por: Chen, Shanshan, et al.
Publicado: (2022)

The neuroprotective potential of endoplasmic reticulum chaperones
por: McLaughlin, Todd, et al.
Publicado: (2015)

Investigation of the neuroprotective effects of crocin via antioxidant activities in HT22 cells and in mice with Alzheimer’s disease
por: Wang, Chunyue, et al.
Publicado: (2019)

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms
por: Isbert, Simone, et al.
Publicado: (2011)

Complete biosynthesis of the phenylethanoid glycoside verbascoside
por: Yang, Yihan, et al.
Publicado: (2023)

Inhibition of autophagy using 3-methyladenine increases cisplatin-induced apoptosis by increasing endoplasmic reticulum stress in U251 human glioma cells
por: ZHANG, RUIJIAN, et al.
Publicado: (2015)

Fluoxetine-mediated inhibition of endoplasmic reticulum stress is involved in the neuroprotective effects of Parkinson’s disease
por: Peng, Tao, et al.
Publicado: (2018)

Transplantation of fecal microbiota from APP/PS1 mice and Alzheimer’s disease patients enhanced endoplasmic reticulum stress in the cerebral cortex of wild-type mice
por: Wang, Fang, et al.
Publicado: (2022)

Endoplasmic reticulum stress regulates epithelial-mesenchymal transition in human lens epithelial cells
por: Zhou, Sheng, et al.
Publicado: (2020)

Relief of endoplasmic reticulum stress enhances DNA damage repair and improves development of pre-implantation embryos
por: Dicks, Naomi, et al.
Publicado: (2017)

Quantification of verbascoside in medicinal species of Phlomis and their genetic relationships
por: Sarkhail, Parisa, et al.
Publicado: (2014)

Verbascoside promotes the regeneration of tyrosine hydroxylase-immunoreactive neurons in the substantia nigra
por: Liang, Jian-qing, et al.
Publicado: (2016)

All roads go to Salubrinal: endoplasmic reticulum stress, neuroprotection and glial scar formation
por: Romero-Ramírez, Lorenzo, et al.
Publicado: (2015)

Neuroprotection Effect of Astragaloside IV from 2-DG-Induced Endoplasmic Reticulum Stress
por: Fu, Yu, et al.
Publicado: (2020)

THE ENDOPLASMIC RETICULUM
por: Palade, George E.
Publicado: (1956)

Hyperoside alleviates toxicity of β-amyloid via endoplasmic reticulum-mitochondrial calcium signal transduction cascade in APP/PS1 double transgenic Alzheimer's disease mice
por: Song, Lin Lin, et al.
Publicado: (2023)

Dehydrodiisoeugenol inhibits colorectal cancer growth by endoplasmic reticulum stress-induced autophagic pathways
por: Li, Changhong, et al.
Publicado: (2021)

Role of Endoplasmic Reticulum Stress in Learning and Memory Impairment and Alzheimer's Disease-Like Neuropathology in the PS19 and APP(Swe) Mouse Models of Tauopathy and Amyloidosis
por: Briggs, Denise Isabelle, et al.
Publicado: (2017)

Neuroprotective Potential of Verbascoside Isolated from Acanthus mollis L. Leaves through Its Enzymatic Inhibition and Free Radical Scavenging Ability
por: Burgos, Carmen, et al.
Publicado: (2020)

Neuroprotective effects of Activin A on endoplasmic reticulum stress-mediated apoptotic and autophagic PC12 cell death
por: Xue, Long-xing, et al.
Publicado: (2017)

In Vitro Human Metabolism and Inhibition Potency of Verbascoside for CYP Enzymes
por: Reid, Anna-Mari, et al.
Publicado: (2019)

Verbascoside Protects Pancreatic β-Cells against ER-Stress
por: Galli, Alessandra, et al.
Publicado: (2020)

Correction: Dehydrodiisoeugenol inhibits colorectal cancer growth by endoplasmic reticulum stress-induced autophagic pathways
por: Li, Changhong, et al.
Publicado: (2023)

Inhibition of endoplasmic reticulum stress is involved in the neuroprotective effect of aFGF in neonatal hypoxic-ischaemic brain injury
por: Hu, Yingying, et al.
Publicado: (2017)

Neuroprotective effects of bajijiasu against cognitive impairment induced by amyloid-β in APP/PS1 mice
por: Cai, Haobin, et al.
Publicado: (2017)

Construction of the endoplasmic reticulum
Publicado: (1989)

Neuroprotective Effects of Leptin on the APP/PS1 Alzheimer’s Disease Mouse Model: Role of Microglial and Neuroinflammation
por: Ma, Jing, et al.
Publicado: (2023)

Wolfram Syndrome iPS Cells: The First Human Cell Model of Endoplasmic Reticulum Disease
por: Urano, Fumihiko
Publicado: (2014)

Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes
por: Bhattacharyya, Raja, et al.
Publicado: (2021)

Corneal Epithelial Wound Healing Promoted by Verbascoside-Based Liposomal Eyedrops
por: Ambrosone, Luigi, et al.
Publicado: (2014)

Teratogenic Effect of Verbascoside, Main Constituent of Lippia citriodora Leaves, in Mice
por: Etemad, Leila, et al.
Publicado: (2016)

Anti-Inflammatory Activity of Iridoids and Verbascoside Isolated from Castilleja tenuiflora
por: Carrillo-Ocampo, Danae, et al.
Publicado: (2013)

Neuroprotective effects of atorvastatin against cerebral ischemia/reperfusion injury through the inhibition of endoplasmic reticulum stress
por: Yang, Jian-wen, et al.
Publicado: (2015)

Correction: Neuroprotective effects of bajijiasu against cognitive impairment induced by amyloid-β in APP/PS1 mice
por: Cai, Haobin, et al.
Publicado: (2018)

Endoplasmic reticulum stress activates telomerase
por: Zhou, Junzhi, et al.
Publicado: (2014)

Glycoprotein Quality Control and Endoplasmic Reticulum Stress
por: Wang, Qian, et al.
Publicado: (2015)

Endoplasmic Reticulum–Mitochondria Contact Sites and Neurodegeneration
por: Xu, Lingna, et al.
Publicado: (2020)

Lipin‐1 determines lung cancer cell survival and chemotherapy sensitivity by regulation of endoplasmic reticulum homeostasis and autophagy
por: Fan, Xueyu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_d4o8bvc9dnpgpqj3g4fnihn9cc