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Early Embryonic Expression of AP-2α Is Critical for Cardiovascular Development

Congenital cardiovascular malformation is a common birth defect incorporating abnormalities of the outflow tract and aortic arch arteries, and mice deficient in the transcription factor AP-2α (Tcfap2a) present with complex defects affecting these structures. AP-2α is expressed in the pharyngeal surf...

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Detalles Bibliográficos
Autores principales: Johnson, Amy-Leigh, Schneider, Jürgen E., Mohun, Timothy J., Williams, Trevor, Bhattacharya, Shoumo, Henderson, Deborah J., Phillips, Helen M., Bamforth, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570199/
https://www.ncbi.nlm.nih.gov/pubmed/32717817
http://dx.doi.org/10.3390/jcdd7030027