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A Novel Small Molecule, 1,3-di-m-tolyl-urea, Inhibits and Disrupts Multispecies Oral Biofilms

An imbalance of homeostasis between the microbial communities and the host system leads to dysbiosis in oral micro flora. DMTU (1,3-di-m-tolyl-urea) is a biocompatible compound that was shown to inhibit Streptococcus mutans biofilm by inhibiting its communication system (quorum sensing). Here, we hy...

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Detalles Bibliográficos
Autores principales: Kalimuthu, Shanthini, Cheung, Becky P.K., Yau, Joyce Y.Y., Shanmugam, Karthi, Solomon, Adline Princy, Neelakantan, Prasanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570320/
https://www.ncbi.nlm.nih.gov/pubmed/32825310
http://dx.doi.org/10.3390/microorganisms8091261