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Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore

The opioid receptors are members of the G-protein-coupled receptor (GPCR) family and are known to modulate a variety of biological functions, including pain perception. Despite considerable advances, the mechanisms by which opioid agonists and antagonists interact with their receptors and exert thei...

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Detalles Bibliográficos
Autores principales: Sarkar, Arijit, Adamska-Bartlomiejczyk, Anna, Piekielna-Ciesielska, Justyna, Wtorek, Karol, Kluczyk, Alicja, Borics, Attila, Janecka, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570497/
https://www.ncbi.nlm.nih.gov/pubmed/32957550
http://dx.doi.org/10.3390/molecules25184260