Synthesis and Evaluation of the Antitumor Activity of Novel 1-(4-Substituted phenyl)-2-ethyl Imidazole Apoptosis Inducers In Vitro

Novel imidazole derivatives were designed, prepared, and evaluated in vitro for antitumor activity. The majority of the tested derivatives showed improved antiproliferative activity compared to the positive control drugs 5-FU and MTX. Among them, compound 4f exhibited outstanding antiproliferative a...

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Detalles Bibliográficos
Autores principales: Li, Zhen-Wang, Zhong, Chun-Yan, Wang, Xiao-Ran, Li, Shi-Nian, Pan, Chun-Yuan, Wang, Xin, Sun, Xian-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570620/
https://www.ncbi.nlm.nih.gov/pubmed/32962127
http://dx.doi.org/10.3390/molecules25184293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570620/
https://www.ncbi.nlm.nih.gov/pubmed/32962127
http://dx.doi.org/10.3390/molecules25184293

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