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Design and Synthesis of a Novel NIR Celecoxib-Based Fluorescent Probe for Cyclooxygenase-2 Targeted Bioimaging in Tumor Cells

Cyclooxygenase-2 (COX-2) imaging agents are potent tools for early cancer diagnosis. Almost all of the COX2 imaging agents using celecoxib as backbone were chemically modified in the position of N-atom in the sulfonamide group. Herein, a novel COX-2 probe (CCY-5) with high targeting ability and a ne...

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Detalles Bibliográficos
Autores principales: Wang, Xinli, Wang, Liye, Xie, Lijun, Xie, Zuoxu, Li, Li, Bui, Dinh, Yin, Taijun, Gao, Song, Hu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570625/
https://www.ncbi.nlm.nih.gov/pubmed/32899627
http://dx.doi.org/10.3390/molecules25184037