Development and Optimization of a High Sensitivity LC-MS/MS Method for the Determination of Hesperidin and Naringenin in Rat Plasma: Pharmacokinetic Approach

The purpose of this study was to develop, optimize, and fully validate a high-sensitivity methodology using UHPLC-MS/MS to simultaneously quantify hesperidin and naringenin in microsamples (100 µL) of murine plasma after intragastric administration of single pure flavonoids and a mixture. The optimi...

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Detalles Bibliográficos
Autores principales: Araujo-León, Jesús Alfredo, Ortiz-Andrade, Rolffy, Vera-Sánchez, Rivelino Armando, Oney-Montalvo, Julio Enrique, Coral-Martínez, Tania Isolina, Cantillo-Ciau, Zulema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570656/
https://www.ncbi.nlm.nih.gov/pubmed/32947773
http://dx.doi.org/10.3390/molecules25184241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570656/
https://www.ncbi.nlm.nih.gov/pubmed/32947773
http://dx.doi.org/10.3390/molecules25184241

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