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Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism

Clear cell foci (CCF) of the liver are considered to be pre-neoplastic lesions of hepatocellular adenomas and carcinomas. They are hallmarked by glycogen overload and activation of AKT (v-akt murine thymoma viral oncogene homolog)/mTOR (mammalian target of rapamycin)-signaling. Here, we report the t...

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Detalles Bibliográficos
Autores principales: Metzendorf, Christoph, Wineberger, Katharina, Rausch, Jenny, Cigliano, Antonio, Peters, Kristin, Sun, Baodong, Mennerich, Daniela, Kietzmann, Thomas, Calvisi, Diego F., Dombrowski, Frank, Ribback, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570661/
https://www.ncbi.nlm.nih.gov/pubmed/32927708
http://dx.doi.org/10.3390/molecules25184141