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LRRK2 Regulates CPT1A to Promote β-Oxidation in HepG2 Cells

Leucine-rich repeat kinase 2 (LRRK2) is involved in lipid metabolism; however, the role of LRRK2 in lipid metabolism to affect non-alcoholic fatty liver disease (NAFLD) is still unclear. In the mouse model of NAFLD induced by a high-fat diet, we observed that LRRK2 was decreased in livers. In HepG2...

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Detalles Bibliográficos
Autores principales: Lin, Chiao-Wei, Peng, Yu-Ju, Lin, Yuan-Yu, Mersmann, Harry John, Ding, Shih-Torng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570678/
https://www.ncbi.nlm.nih.gov/pubmed/32916992
http://dx.doi.org/10.3390/molecules25184122